Human Immunodeficiency Virus Type 1 Tat Accelerates Kaposi Sarcoma-Associated Herpesvirus Kaposin A-Mediated Tumorigenesis of Transformed Fibroblasts In Vitro as well as in Nude and Immunocompetent Mice

Kaposi sarcoma-associated herpesvirus (KSHV) is necessary but not sufficient to cause Kaposi sarcoma (KS). Coinfection with human immunodeficiency virus type 1 (HIV-1), in the absence of antiretroviral suppressive therapy, drastically increases the risk of KS. Previously, we identified that HIV-1 tr...

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Bibliographic Details
Main Authors: Xiuying Chen, Lin Cheng, Xuemei Jia, Yi Zeng, Shuihong Yao, Zhigang Lv, Di Qin, Xin Fang, Yongliang Lei, Chun Lu
Format: Article
Language:English
Published: Elsevier 2009-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800961