Pareto optimality between growth-rate and lag-time couples metabolic noise to phenotypic heterogeneity in Escherichia coli
It is unclear how noise in gene expression propagates to phenotypic heterogeneity in clonal bacterial populations. Here, the authors explore how variability in central sugar metabolism in E. coli can mediate and promote population diversification.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-23522-0 |