Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization

Biological processes can be regulated via oligomerization of macromolecules into high-order symmetric structures. Here, authors reported high-order structure of RNA polymerase and its role in regulation of gene expression in pathogenic bacterium.

Bibliographic Details
Main Authors: Zakia Morichaud, Stefano Trapani, Rishi K. Vishwakarma, Laurent Chaloin, Corinne Lionne, Joséphine Lai-Kee-Him, Patrick Bron, Konstantin Brodolin
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36113-y