Serum HPV16 E7 Oncoprotein Is a Recurrence Marker of Oropharyngeal Squamous Cell Carcinomas

Serum HPV16 E7 Oncoprotein Is a Recurrence Marker of Oropharyngeal Squamous Cell Carcinomas

Despite improved prognosis for many HPV-positive head and neck squamous cell carcinomas (HNSCCs), some cases are still marked by recurrence and metastasis. Our study aimed to identify novel biomarkers for patient stratification. Classical HPV markers: HPV-DNA, p16 and HPV mRNA expression were studie...

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Bibliographic Details
Main Authors: Lucia Oton-Gonzalez, John Charles Rotondo, Carmen Lanzillotti, Elisa Mazzoni, Ilaria Bononi, Maria Rosa Iaquinta, Luca Cerritelli, Nicola Malagutti, Andrea Ciorba, Chiara Bianchini, Stefano Pelucchi, Mauro Tognon, Fernanda Martini
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
human papillomavirus
oropharyngeal squamous cell carcinoma
treatment de-escalation
patient stratification
E7 oncoprotein
HPV DNA
Online Access:https://www.mdpi.com/2072-6694/13/13/3370

Internet

https://www.mdpi.com/2072-6694/13/13/3370

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