Evaluation of Hydrogel Suppositories for Delivery of 5-Aminolevulinic Acid and Hematoporphyrin Monomethyl Ether to Rectal Tumors

Evaluation of Hydrogel Suppositories for Delivery of 5-Aminolevulinic Acid and Hematoporphyrin Monomethyl Ether to Rectal Tumors

We evaluated the potential utility of hydrogels for delivery of the photosensitizing agents 5-aminolevulinic acid (ALA) and hematoporphyrin monomethyl ether (HMME) to rectal tumors. Hydrogel suppositories containing ALA or HMME were administered to the rectal cavity of BALB/c mice bearing subcutaneo...

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Bibliographic Details
Main Authors: Xuying Ye, Huijuan Yin, Yu Lu, Haixia Zhang, Han Wang
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Molecules
Subjects:
photosensitizer
drug delivery
photodynamic therapy
hematoporphyrin monomethyl ether
5-aminolevulinic acid
rectal cancer
Online Access:http://www.mdpi.com/1420-3049/21/10/1347

Internet

http://www.mdpi.com/1420-3049/21/10/1347

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