Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB

Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB

BackgroundCancer cells activate different immune checkpoint (IC) pathways in order to evade immunosurveillance. Immunotherapies involving ICs either block or stimulate these pathways and enhance the efficiency of the immune system to recognize and attack cancer cells. In this way, the development of...

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Bibliographic Details
Main Authors: Taciana Manso, Anjana Kushwaha, Nika Abdollahi, Patrice Duroux, Véronique Giudicelli, Sofia Kossida
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
IMGT
monoclonal antibodies
immune checkpoints
oncology
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1129323/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1129323/full

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