Development of a Simple and Quick Method to Assess Base Editing in Human Cells

Development of a Simple and Quick Method to Assess Base Editing in Human Cells

Base editing is a form of genome editing that can directly convert a single base (C or A) to another base (T or G), which is of great potential in biomedical applications. The broad application of base editing is limited by its low activity and specificity, which still needs to be resolved. To addre...

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Bibliographic Details
Main Authors: Xiujuan Lv, Kairui Qiu, Tianxiang Tu, Xiaoxue He, Yuchen Peng, Jinbin Ye, Junhao Fu, Ruzhi Deng, Yuqin Wang, Jinyu Wu, Changbao Liu, Junzhao Zhao, Feng Gu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Adenine base editor
Cytosine base editor
Detection
Genome editing
Method
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300950

Internet

http://www.sciencedirect.com/science/article/pii/S2162253120300950

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