A Selective Pharmacophore Model for β2-Adrenoceptor Agonists

β2-Adrenoceptor selectivity is an important consideration in drug design in order to minimize the possibility of side effects. A selective pharmacophore model was developed based on a series of selective β2-adrenoceptor agonists. The best pharmacophore hypothesis consisted of five chemical features...

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Bibliographic Details
Main Authors: Mao-Sheng Cheng, Li Pan, Jian Wang, Rui-Juan Xing
Format: Article
Language:English
Published: MDPI AG 2009-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/14/11/4486/