Persistence of botulinum neurotoxin a subtypes 1-5 in primary rat spinal cord cells.

Botulinum neurotoxins (BoNTs) are the most poisonous substances known and cause the severe disease botulism. BoNTs have also been remarkably effective as therapeutics in treating many neuronal and neuromuscular disorders. One of the hallmarks of BoNTs, particularly serotype A, is its long persistenc...

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Bibliographic Details
Main Authors: Regina Clare Meyer Whitemarsh, William Howard Tepp, Eric Arthur Johnson, Sabine Pellett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3937374?pdf=render