A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions
RecA protein mediates homologous recombination repair in bacteria through assembly of long helical filaments on ssDNA in an ATP-dependent manner. RecX, an important negative regulator of RecA, is known to inhibit RecA activity by stimulating the disassembly of RecA nucleoprotein filaments. Here we u...
Main Authors: | Aleksandr Alekseev, Georgii Pobegalov, Natalia Morozova, Alexey Vedyaykin, Galina Cherevatenko, Alexander Yakimov, Dmitry Baitin, Mikhail Khodorkovskii |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/78409 |
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