Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension

Identification of ACKR4 as an immune checkpoint in pulmonary arterial hypertension

ObjectiveInflammation is recognized as a contributor in the development of pulmonary arterial hypertension (PAH), and the recruitment and functional capacity of immune cells are well-orchestrated by chemokines and their receptors. This study is aimed at identification of critical chemokines in the p...

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Bibliographic Details
Main Authors: Chen-Yu Jiang, Li-Wei Wu, Yi-Wei Liu, Bei Feng, Lin-Cai Ye, Xu Huang, Yang-Yang He, Yi Shen, Yi-Fan Zhu, Xing-Liang Zhou, Dai-Ji Jiang, Hai-Kun Qi, Hao Zhang, Yi Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
pulmonary arterial hypertension
atypical chemokine receptor 4
transcriptomics
chemokines
immune
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1153573/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1153573/full

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