Evaluation of Recombinant Botulinum Neurotoxin Type A1 Efficacy in Peripheral Inflammatory Pain in Mice

Evaluation of Recombinant Botulinum Neurotoxin Type A1 Efficacy in Peripheral Inflammatory Pain in Mice

Well-established efficacy of botulinum neurotoxin type A (BoNT/A) in aesthetic dermatology and neuromuscular hyperactivity disorders relies on canonical interruption of acetylcholine neurotransmission at the neuromuscular junction at the site of the injection. The mechanisms and the site of activity...

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Bibliographic Details
Main Authors: Beatrice Oehler, Cindy Périer, Vincent Martin, Amy Fisher, Stéphane Lezmi, Mikhail Kalinichev, Stephen B. McMahon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
inflammation
nociception
analgesia
GCaMP
in vivo calcium imaging
hyperalgesia
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.909835/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.909835/full

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