Cytotoxic capacity of a novel glycosylated antitumor ether lipid in chemotherapy-resistant high grade serous ovarian cancer in vitro and in vivo

Chemotherapy resistant high grade serous ovarian cancer remains a clinically intractable disease with a high rate of mortality. We tested a novel glycosylated antitumor ether lipid called l-Rham to assess the in vitro and in vivo efficacy on high grade serous ovarian cancer cell lines and patient sa...

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Bibliographic Details
Main Authors: Mark W Nachtigal, Paris Musaphir, Shiv Dhiman, Alon D Altman, Frank Schweizer, Gilbert Arthur
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321001959