A flow cytometry-based neutralization assay for simultaneous evaluation of blocking antibodies against SARS-CoV-2 variants

A flow cytometry-based neutralization assay for simultaneous evaluation of blocking antibodies against SARS-CoV-2 variants

Vaccines against SARS-CoV-2 have alleviated infection rates, hospitalization and deaths associated with COVID-19. In order to monitor humoral immunity, several serology tests have been developed, but the recent emergence of variants of concern has revealed the need for assays that predict the neutra...

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Bibliographic Details
Main Authors: Leire Egia-Mendikute, Alexandre Bosch, Endika Prieto-Fernández, Laura Vila-Vecilla, Samanta Romina Zanetti, So Young Lee, Borja Jiménez-Lasheras, Ana García del Río, Asier Antoñana-Vildosola, Ander de Blas, Paloma Velasco-Beltrán, Marina Serrano-Maciá, Paula Iruzubieta, Majid Mehrpouyan, Edward M. Goldberg, Scott J. Bornheimer, Nieves Embade, María L. Martínez-Chantar, Marcos López-Hoyos, José M. Mato, Óscar Millet, Asís Palazón
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
antibodies
flow cytometry
neutralization
beads array
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1014309/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1014309/full

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