Feedback Activation of STAT3 Confers Resistance of HER2-positive Breast Cancer Cells to Lapatinib
Objective To explore the role of interleukin-6 (IL-6) in lapatinib-resistant HER2-positive breast cancer cells BT-474. Methods Lapatinib-resistant BT-474 (BT-474R) cells were established. Western blot was used to test P-gp expression. The growth inhibition rate(IC50) was tested by MTT assay, and Cas...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Magazine House of Cancer Research on Prevention and Treatment
2019-04-01
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| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1410.htm |