Quantitative nuclear phenotype signatures predict nodal disease in oral squamous cell carcinoma.

<h4>Background</h4>Early-stage oral squamous cell carcinoma (OSCC) patients have a one-in-four risk of regional metastasis (LN+), which is also the most significant prognostic factor for survival. As there are no validated biomarkers for predicting LN+ in early-stage OSCC, elective neck...

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Bibliographic Details
Main Authors: Kelly Yi Ping Liu, Sarah Yuqi Zhu, Alan Harrison, Zhao Yang Chen, Martial Guillaud, Catherine F Poh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0259529