Engineering Macrophages via Nanotechnology and Genetic Manipulation for Cancer Therapy

Engineering Macrophages via Nanotechnology and Genetic Manipulation for Cancer Therapy

Macrophages play critical roles in tumor progression. In the tumor microenvironment, macrophages display highly diverse phenotypes and may perform antitumorigenic or protumorigenic functions in a context-dependent manner. Recent studies have shown that macrophages can be engineered to transport drug...

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Bibliographic Details
Main Authors: Xiaoling Ding, Xinchen Sun, Huihui Cai, Lei Wu, Ying Liu, Yu Zhao, Dingjingyu Zhou, Guiping Yu, Xiaorong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
macrophages
bioengineering
nanotechnology
cancer immunotherapy
chimeric antigen receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.786913/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.786913/full

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