The Mechanisms of Altered Blood–Brain Barrier Permeability in CD19 CAR T–Cell Recipients

Cluster of differentiation 19 (CD19) chimeric antigen receptor (CAR) T cells are a highly effective immunotherapy for relapsed and refractory B-cell malignancies, but their utility can be limited by the development of immune effector cell-associated neurotoxicity syndrome (ICANS). The recent discove...

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Bibliographic Details
Main Authors: Soniya N. Pinto, Giedre Krenciute
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/25/1/644