Structure-based engineering of a novel CD3ε-targeting antibody for reduced polyreactivity
ABSTRACTBispecific antibodies continue to represent a growth area for antibody therapeutics, with roughly a third of molecules in clinical development being T-cell engagers that use an anti-CD3 binding arm. CD3 antibodies possessing cross-reactivity with cynomolgus monkey typically recognize a highl...
| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Taylor & Francis Group
2023-12-01
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| coleção: | mAbs |
| Assuntos: | |
| Acesso em linha: | https://www.tandfonline.com/doi/10.1080/19420862.2023.2189974 |