Current and Future Perspectives for Chimeric Antigen Receptor T Cells Development in Poland

Current and Future Perspectives for Chimeric Antigen Receptor T Cells Development in Poland

Chimeric antigen receptor T (CAR-T) cells are genetically modified autologous T cells that have revolutionized the treatment of relapsing and refractory haematological malignancies. In this review we present molecular pathways involved in the activation of CAR-T cells, describe in details the struct...

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Bibliographic Details
Main Authors: Tomasz J. Ślebioda, Marcin Stanisławowski, Lucyna Kaszubowska, Jan M. Zaucha, Michał A. Żmijewski
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
CAR-T
CAR-NK
chimeric antigen receptor
tisagenlecleucel
axicabtagene ciloleucel
brexucabtagene autoleucel
Online Access:https://www.mdpi.com/2227-9059/10/11/2912

Internet

https://www.mdpi.com/2227-9059/10/11/2912

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