Sleep traits causally affect epigenetic age acceleration: a Mendelian randomization study

Abstract Sleep disorders (SDs) are a common issue in the elderly. Epigenetic clocks based on DNA methylation (DNAm) are now considered highly accurate predictors of the aging process and are associated with age-related diseases. This study aimed to investigate the causal relationship between sleep t...

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Bibliographic Details
Main Authors: Wen Zhao, Shiyao Yu, Yan Xu, Huijuan Liao, Daiyi Chen, Ting Lu, Zhixuan Ren, Lijuan Ge, Jianhui Liu, Jingbo Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-84957-1