Susceptibility to chronic mucus hypersecretion, a genome wide association study.

Chronic mucus hypersecretion (CMH) is associated with an increased frequency of respiratory infections, excess lung function decline, and increased hospitalisation and mortality rates in the general population. It is associated with smoking, but it is unknown why only a minority of smokers develops...

Full description

Bibliographic Details
Main Authors: Akkelies E Dijkstra, Joanna Smolonska, Maarten van den Berge, Ciska Wijmenga, Pieter Zanen, Marjan A Luinge, Mathieu Platteel, Jan-Willem Lammers, Magnus Dahlback, Kerrie Tosh, Pieter S Hiemstra, Peter J Sterk, Avi Spira, Jorgen Vestbo, Borge G Nordestgaard, Marianne Benn, Sune F Nielsen, Morten Dahl, W Monique Verschuren, H Susan J Picavet, Henriette A Smit, Michael Owsijewitsch, Hans U Kauczor, Harry J de Koning, Eva Nizankowska-Mogilnicka, Filip Mejza, Pawel Nastalek, Cleo C van Diemen, Michael H Cho, Edwin K Silverman, James D Crapo, Terri H Beaty, David A Lomas, Per Bakke, Amund Gulsvik, Yohan Bossé, Ma'en Obeidat, Daan W Loth, Lies Lahousse, Fernando Rivadeneira, Andre G Uitterlinden, Andre Hofman, Bruno H Stricker, Guy G Brusselle, Cornelia M van Duijn, Uilke Brouwer, Gerard H Koppelman, Judith M Vonk, Martijn C Nawijn, Harry J M Groen, Wim Timens, H Marike Boezen, Dirkje S Postma, LifeLines Cohort study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979657?pdf=render