FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway

FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway

Triple-negative breast cancer (TNBC) lacks effective therapeutic targets and has a poor prognosis, easy recurrence and metastasis. It is urgent and important to explore TNBC treatment targets. Through mass spectrometry combined with qRT-PCR validation in luminal A cells and TNBC cells, high-content...

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Bibliographic Details
Main Authors: Yin Liyang, Cao Renxian, Liu Zhuoqing, Luo Gang, Li Yu, Zhou Xiaolong, Chen Xiguang, Wu Ying, He Jun, Zu Xuyu, Shen Yingying
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-09-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
FUNDC2
GLI1
triple-negative breast cancer (TNBC)
therapeutic target
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023142

Internet

https://www.sciengine.com/doi/10.3724/abbs.2023142

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