A top-down measure of gene-to-gene coordination for analyzing cell-to-cell variability

Abstract Recent technological advances, such as single-cell RNA sequencing (scRNA-seq), allow the measurement of gene expression profiles of individual cells. These expression profiles typically exhibit substantial variations even across seemingly homogeneous populations of cells. Two main different...

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Bibliographic Details
Main Authors: Dana Vaknin, Guy Amit, Amir Bashan
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90353-w