Loss of ATRX does not confer susceptibility to osteoarthritis.

The chromatin remodelling protein ATRX is associated with the rare genetic disorder ATR-X syndrome. This syndrome includes developmental delay, cognitive impairment, and a variety of skeletal deformities. ATRX plays a role in several basic chromatin-mediated cellular events including DNA replication...

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Bibliographic Details
Main Authors: Lauren A Solomon, Bailey A Russell, David Makar, Nathalie G Bérubé, Frank Beier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3875582?pdf=render