Targeting chemoresistant senescent pancreatic cancer cells improves conventional treatment efficacy

Abstract Pancreatic cancer is one of the deadliest cancers owing to its late diagnosis and of the strong resistance to available treatments. Despite a better understanding of the disease in the last two decades, no significant improvement in patient care has been made. Senescent cells are characteri...

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Bibliographic Details
Main Authors: Sara Jaber, Marine Warnier, Christopher Leers, Mathieu Vernier, Delphine Goehrig, Jean-Jacques Médard, David Vindrieux, Dorian V. Ziegler, David Bernard
Format: Article
Language:English
Published: Springer 2023-02-01
Series:Molecular Biomedicine
Subjects:
Online Access:https://doi.org/10.1186/s43556-023-00116-4