Unique Properties of Heme Binding of the <i>Porphyromonas gingivalis</i> HmuY Hemophore-like Protein Result from the Evolutionary Adaptation of the Protein Structure

To acquire heme, <i>Porphyromonas gingivalis</i> uses a hemophore-like protein (HmuY). HmuY sequesters heme from host hemoproteins or heme-binding proteins produced by cohabiting bacteria, and delivers it to the TonB-dependent outer-membrane receptor (HmuR). Although three-dimensional pr...

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Bibliographic Details
Main Authors: Joanna Kosno, Klaudia Siemińska, Teresa Olczak
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/5/1703