Different immunological mechanisms between AQP4 antibody-positive and MOG antibody-positive optic neuritis based on RNA sequencing analysis of whole blood

Different immunological mechanisms between AQP4 antibody-positive and MOG antibody-positive optic neuritis based on RNA sequencing analysis of whole blood

PurposeTo compare the different immunological mechanisms between aquaporin 4 antibody-associated optic neuritis (AQP4-ON) and myelin oligodendrocyte glycoprotein antibody-associated optic neuritis (MOG-ON) based on RNA sequencing (RNA-seq) of whole blood.MethodsWhole blood was collected from seven h...

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Bibliographic Details
Main Authors: Xuelian Chen, Libo Cheng, Ying Pan, Peng Chen, Yidan Luo, Shiyi Li, Wenjun Zou, Ke Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
optic neuritis
aquaporin 4
myelin oligodendrocyte glycoprotein
RNA-Seq
toll-like receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1095966/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1095966/full

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