Association of rs16917496 polymorphism at the miR-502 binding site in the SET8 3'UTR with the risk of Prostate Cancer and benign prostatic hyperplasia

Association of rs16917496 polymorphism at the miR-502 binding site in the SET8 3'UTR with the risk of Prostate Cancer and benign prostatic hyperplasia

<h2>Background: MicroRNAs (miRNAs) can bind to the 3'-untranslated regions (UTRs) of messenger RNAs, where they interfere with translation and thereby regulate cell differentiation, apoptosis, and tumorigenesis. Genetic polymorphisms in the 3'-UTRs targeted by miRNAs alter the streng...

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Bibliographic Details
Main Authors: Mahsa Haj Manochehri, Faezeh Azizi, Mahnoosh Rahimi, Mir Davood Omrani
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2018-04-01
Series:Novelty in Biomedicine
Subjects:
Prostate Cancer, Benign Prostatic Hyperplasia, Single Nucleotide Polymorphism
Online Access:http://journals.sbmu.ac.ir/nbm/article/view/18292

Internet

http://journals.sbmu.ac.ir/nbm/article/view/18292

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