Non-Reproducibility of Oral Rotenone as a Model for Parkinson’s Disease in Mice

Non-Reproducibility of Oral Rotenone as a Model for Parkinson’s Disease in Mice

Oral rotenone has been proposed as a model for Parkinson’s disease (PD) in mice. To establish the model in our lab and study complex behavior we followed a published treatment regimen. C57BL/6 mice received 30 mg/kg body weight of rotenone once daily via oral administration for 4 and 8 weeks. Motor...

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Bibliographic Details
Main Authors: Ellen Niederberger, Annett Wilken-Schmitz, Christine Manderscheid, Yannick Schreiber, Robert Gurke, Irmgard Tegeder
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
rotenone
oral
mice
motor behavior
synuclein
Online Access:https://www.mdpi.com/1422-0067/23/20/12658

Internet

https://www.mdpi.com/1422-0067/23/20/12658

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