Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain

Phospholipase A2(PLA2) is the key enzyme that initiates the arachidonic acid cascade, which leads to the generation of multiple eicosanoid products. Many of these products are believed to play an important role in the inflammatory process. Activation of PLA2is observed under pathological conditions...

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Bibliographic Details
Main Authors: Diane T. Stephenson, Cynthia A. Lemere, Dennis J. Selkoe, James A. Clemens
Format: Article
Language:English
Published: Elsevier 1996-02-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996196900054