Revisiting Non-BRCA1/2 Familial Whole Exome Sequencing Datasets Implicates NCK1 as a Cancer Gene

Revisiting Non-BRCA1/2 Familial Whole Exome Sequencing Datasets Implicates NCK1 as a Cancer Gene

Through linkage and candidate gene screening, many breast cancer (BC) predisposition genes have been identified in the past 20 years. However, the majority of genetic risks that contribute to familial BC remains undetermined. In this study, we revisited whole exome sequencing datasets from non-BRCA1...

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Bibliographic Details
Main Authors: Jie Yin, Kai Wu, Qingyang Ma, Hang Dong, Yufei Zhu, Landian Hu, Xiangyin Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Genetics
Subjects:
breast cancer
non-BRCA1/2
NCK1
predisposition gene
invasion
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00527/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00527/full

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