Different threats posed by two major mobilized colistin resistance genes — mcr-1.1 and mcr-3.1 — revealed through comparative genomic analysis

Different threats posed by two major mobilized colistin resistance genes — mcr-1.1 and mcr-3.1 — revealed through comparative genomic analysis

ABSTRACT: Objectives: Global spread of mobilized colistin resistance gene (mcr)-carrying Escherichia coli poses serious threats to public health. This study aimed to provide insights into different threats posed by two major mcr variants: mcr-1.1 and mcr-3.1. Methods: Genetic backgrounds and charac...

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Bibliographic Details
Main Authors: Soomin Lee, Jae-Uk An, Woo-Hyun Kim, Saehah Yi, JunBum Lee, Seongbeom Cho
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Colistin
mcr-1.1-cassette
mcr-3.1-cassette
Mobile genetic elements
Multidrug resistance
Horizontal transfer
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716522003678

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http://www.sciencedirect.com/science/article/pii/S2213716522003678

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