Non-Human Primate iPSC Generation, Cultivation, and Cardiac Differentiation under Chemically Defined Conditions

Non-Human Primate iPSC Generation, Cultivation, and Cardiac Differentiation under Chemically Defined Conditions

Non-human primates (NHP) are important surrogate models for late preclinical development of advanced therapy medicinal products (ATMPs), including induced pluripotent stem cell (iPSC)-based therapies, which are also under development for heart failure repair. For effective heart repair by remuscular...

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Bibliographic Details
Main Authors: Michael Stauske, Ignacio Rodriguez Polo, Wadim Haas, Debbra Yasemin Knorr, Thomas Borchert, Katrin Streckfuss-Bömeke, Ralf Dressel, Iris Bartels, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Rüdiger Behr
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
induced pluripotent stem cell
cellular reprogramming
cardiac differentiation
Wnt signaling
translation
rhesus monkey
Online Access:https://www.mdpi.com/2073-4409/9/6/1349

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https://www.mdpi.com/2073-4409/9/6/1349

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