Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT.

BACKGROUND: Ursolic acid (UA), a pentacyclic triterpenoid carboxylic acid, is the major component of many plants including apples, basil, cranberries, peppermint, rosemary, oregano and prunes and has been reported to possess antioxidant and anti-tumor properties. These properties of UA have been att...

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Bibliographic Details
Main Authors: Rahul Checker, Santosh K Sandur, Deepak Sharma, Raghavendra S Patwardhan, S Jayakumar, Vineet Kohli, Gautam Sethi, Bharat B Aggarwal, Krishna B Sainis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282718?pdf=render