Bifunctional Catalysis: Direct Reductive Amination of Aliphatic Ketones with an Iridium-Phosphate Catalyst

Bifunctional Catalysis: Direct Reductive Amination of Aliphatic Ketones with an Iridium-Phosphate Catalyst

Chiral amines are one of the ubiquitous functional groups in fine chemical, pharmaceutical and agrochemical products, and the most convenient, economical, and eco-benign synthetic pathway to these amines is direct asymmetric reductive amination (DARA) of prochiral ketones. This paper shows that a wi...

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Bibliographic Details
Main Authors: Barbara Villa-Marcos, Chaoqun Li, Keith R. Mulholland, Philip J. Hogan, Jianliang Xiao
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Molecules
Subjects:
reductive amination
asymmetric hydrogenation
bifunctional catalyst
aliphatic ketones
chiral amines
Online Access:http://www.mdpi.com/1420-3049/15/4/2453/

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http://www.mdpi.com/1420-3049/15/4/2453/

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