COL10A1-DDR2 axis promotes the progression of pancreatic cancer by regulating MEK/ERK signal transduction

COL10A1-DDR2 axis promotes the progression of pancreatic cancer by regulating MEK/ERK signal transduction

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant tumors with a poor prognosis. Type X collagen α 1 chain (COL10A1), a member of the collagen family, is a gene associated with the progression of a variety of human tumors, but the specific function and molecular mechanism of...

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Bibliographic Details
Main Authors: Zhihui Wen, Jingbo Sun, Junjie Luo, Yun Fu, Yue Qiu, Yanyan Li, Yangwei Xu, Hongmei Wu, Qingling Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
COL10A1
DDR2
pancreatic cancer
metastasis
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1049345/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1049345/full

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