Small molecule drug discovery for glioblastoma treatment based on bioinformatics and cheminformatics approaches

Small molecule drug discovery for glioblastoma treatment based on bioinformatics and cheminformatics approaches

Background: Glioblastoma (GBM) is a common and highly aggressive brain tumor with a poor prognosis for patients. It is urgently needed to identify potential small molecule drugs that specifically target key genes associated with GBM development and prognosis.Methods: Differentially expressed genes (...

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Bibliographic Details
Main Authors: Liya Feng, Sha Zhu, Jian Ma, Jing Huang, Xiaoyan Hou, Qian Qiu, Tingting Zhang, Meixia Wan, Juan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Pharmacology
Subjects:
glioblastoma
multi-omics data
bioinformatics
therapeutic agents
ADMET
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1389440/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1389440/full

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