Tyrosine 146 of the Human Na<sup>+</sup>/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes

Tyrosine 146 of the Human Na<sup>+</sup>/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes

Na<sup>+</sup>/taurocholate cotransporting polypeptide (NTCP, gene symbol SLC10A1) is a hepatic bile acid uptake carrier participating in the enterohepatic circulation of bile acids. Apart from its transporter function, NTCP acts as the high-affinity liver-specific receptor for the hepat...

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Bibliographic Details
Main Authors: Dariusz Zakrzewicz, Regina Leidolf, Sebastian Kunz, Simon Franz Müller, Anita Neubauer, Silke Leiting, Nora Goldmann, Felix Lehmann, Dieter Glebe, Joachim Geyer
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
bile acid
HBV
infection
NTCP
preS1
receptor
Online Access:https://www.mdpi.com/1999-4915/14/6/1259

Internet

https://www.mdpi.com/1999-4915/14/6/1259

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