Identification of Specific Biomarkers and Pathways in the Treatment Response of Infliximab for Inflammatory Bowel Disease: In-Silico Analysis

Background: Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract. In biological therapy, infliximab became the first anti-tumor necrosis factor (TNF) agent approved for IBD. Despite this success, infliximab is expensive, often ineffective, and assoc...

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Bibliographic Details
Main Authors: Rachid Kaddoura, Hardik Ghelani, Fatma Alqutami, Hala Altaher, Mahmood Hachim, Reem Kais Jan
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/3/680