GGAA microsatellites of NR0B1 promoter region in Ewing's sarcoma patients and healthy individuals from a south Brazilian population

GGAA microsatellites of NR0B1 promoter region in Ewing's sarcoma patients and healthy individuals from a south Brazilian population

Introduction: The very aggressive soft tissue and bone pediatric tumor Ewing’s sarcoma (ES) is caused in most cases by the chromosomal translocation t(11;22)(q24;q12), which encodes an aberrant chimeric transcription factor (EWS-FLI1) that regulates target genes, including the critical oncogene NR0...

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Bibliographic Details
Main Authors: Rodrigo Rosa de Stefani, Elisa Cristina de Toni, Caroline Brunetto de Farias, André Tesainer Brunetto, Algemir Lunardi Brunetto, Rafael Roesler, Clarice Sampaio Alho, Deise Cristine Friedrich
Format: Article
Language:English
Published: Instituto Nacional de Câncer (INCA) 2022-03-01
Series:Revista Brasileira de Cancerologia
Subjects:
Ewing’s sarcoma, NR0B1, GGAA microsatellites, cancer susceptibility, oncogene
Online Access:https://rbc.inca.gov.br/index.php/revista/article/view/2350

Internet

https://rbc.inca.gov.br/index.php/revista/article/view/2350

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