The Long Non-Coding RNA <i>Prader Willi/Angelman Region RNA5</i> (<i>PAR5</i>) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity

The Long Non-Coding RNA <i>Prader Willi/Angelman Region RNA5</i> (<i>PAR5</i>) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity

Anaplastic thyroid carcinoma (ATC) represents one the most aggressive neoplasias in humans, and, nowadays, limited advances have been made to extend the survival and reduce the mortality of ATC. Thus, the identification of molecular mechanism underlying its progression is needed. Here, we evaluated...

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Bibliographic Details
Main Authors: Simona Pellecchia, Romina Sepe, Myriam Decaussin-Petrucci, Cristina Ivan, Masayoshi Shimizu, Carmela Coppola, Domenico Testa, George Adrian Calin, Alfredo Fusco, Pierlorenzo Pallante
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
anaplastic thyroid carcinoma
ezh2
<i>par5</i>
long non-coding rna
Online Access:https://www.mdpi.com/2072-6694/12/1/235

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https://www.mdpi.com/2072-6694/12/1/235

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