ESTRATÉGIAS DE SÍNTESE NA DESCOBERTA DE FÁRMACOS: O EMPREGO DA SÍNTESE ORIENTADA PELA DIVERSIDADE ESTRUTURAL
Drug discovery often involves screening synthetic small molecules for their ability to bind to a macromolecular target. Target-Oriented Synthesis of a specific compound or a focused library can be planned combining retrosynthetic analysis and rational drug design. Biologically active molecules also...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
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| Series: | Química Nova |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422016000800995&lng=en&tlng=en |