In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells.
In the rat islets γ-aminobutyric acid (GABA) is produced by the β-cells and, at least, the α-cells express the GABA(A) receptors (GABA(A) channels). In this study, we examined in intact islets if the interstitial GABA activated the GABA(A) receptors. We used the patch-clamp technique to record whole...
| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artikel |
| Språk: | English |
| Publicerad: |
Public Library of Science (PLoS)
2013-01-01
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| Serie: | PLoS ONE |
| Länkar: | http://europepmc.org/articles/PMC3691163?pdf=render |