Neurokinin receptor mechanisms in forebrain medial septum modulate nociception in the formalin model of inflammatory pain
Abstract The present study has explored the hypothesis that neurokinin1 receptors (NK1Rs) in medial septum (MS) modulate nociception evoked on hind paw injection of formalin. Indeed, the NK1Rs in MS are localized on cholinergic neurons which have been implicated in nociception. In anaesthetized rat,...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-12-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-03661-6 |