Neurokinin receptor mechanisms in forebrain medial septum modulate nociception in the formalin model of inflammatory pain

Abstract The present study has explored the hypothesis that neurokinin1 receptors (NK1Rs) in medial septum (MS) modulate nociception evoked on hind paw injection of formalin. Indeed, the NK1Rs in MS are localized on cholinergic neurons which have been implicated in nociception. In anaesthetized rat,...

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Bibliographic Details
Main Authors: Si Yun Ng, Mohammed Zacky Ariffin, Sanjay Khanna
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-03661-6