CCR5del32 genotype in human enteroviral cardiomyopathy leads to spontaneous virus clearance and improved outcome compared to wildtype CCR5

CCR5del32 genotype in human enteroviral cardiomyopathy leads to spontaneous virus clearance and improved outcome compared to wildtype CCR5

Abstract Background Enteroviral cardiomyopathy is a life-threatening disease, and detection of enterovirus (EV) RNA in the initial endomyocardial biopsy is associated with adverse prognosis and increased mortality. Some patients with EV infection may spontaneously eliminate the virus and recover, wh...

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Bibliographic Details
Main Authors: Dirk Lassner, Christine S. Siegismund, Uwe Kühl, Maria Rohde, Andrea Stroux, Felicitas Escher, Heinz-Peter Schultheiss
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Translational Medicine
Subjects:
Cardiomyopathy
CCR5del32 genotype
Coxsackievirus
Enterovirus
Interferon-beta therapy
Online Access:http://link.springer.com/article/10.1186/s12967-018-1610-8

Internet

http://link.springer.com/article/10.1186/s12967-018-1610-8

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