BMAL1 controls the diurnal rhythm and set point for electrical seizure threshold in mice

The epilepsies are a heterogeneous group of neurological diseases defined by the occurrence of unprovoked seizures which, in many cases, are correlated with diurnal rhythms. In order to gain insight into the biological mechanisms controlling this phenomenon, we characterized time-of-day effects on...

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Bibliographic Details
Main Authors: Jason Robert Gerstner, George eSmith, Olivia eLenz, Isaac J Perron, Russell J Buono, Thomas N Ferraro
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00121/full