BMAL1 controls the diurnal rhythm and set point for electrical seizure threshold in mice
The epilepsies are a heterogeneous group of neurological diseases defined by the occurrence of unprovoked seizures which, in many cases, are correlated with diurnal rhythms. In order to gain insight into the biological mechanisms controlling this phenomenon, we characterized time-of-day effects on...
Main Authors: | Jason Robert Gerstner, George eSmith, Olivia eLenz, Isaac J Perron, Russell J Buono, Thomas N Ferraro |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-06-01
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Series: | Frontiers in Systems Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00121/full |
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