Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.

Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.

Type 2 diabetes (T2D) has become a major health problem worldwide. Skeletal muscle (SKM) is the key tissue for whole-body glucose disposal and utilization. New drugs aimed at improving insulin sensitivity of SKM would greatly expand available therapeutic options. β-arrestin-1 and -2 (Barr1 and Barr2...

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Main Authors: Jaroslawna Meister, Derek B J Bone, Grzegorz Godlewski, Ziyi Liu, Regina J Lee, Sergey A Vishnivetskiy, Vsevolod V Gurevich, Danielle Springer, George Kunos, Jürgen Wess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008424

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https://doi.org/10.1371/journal.pgen.1008424

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