A redox-responsive dihydroartemisinin dimeric nanoprodrug for enhanced antitumor activity
Abstract Redox-responsive drug delivery system emerges as a hopeful platform for tumor treatment. Dihydroartemisinin (DHA) has been investigated as an innovative tumor therapeutic agent. Herein, a DHA dimeric prodrug bridged with disulfide bond as linker (DHA2-SS) has been designed and synthesized....
Main Authors: | , , , , , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
BMC
2021-12-01
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סדרה: | Journal of Nanobiotechnology |
נושאים: | |
גישה מקוונת: | https://doi.org/10.1186/s12951-021-01200-z |