A redox-responsive dihydroartemisinin dimeric nanoprodrug for enhanced antitumor activity

Abstract Redox-responsive drug delivery system emerges as a hopeful platform for tumor treatment. Dihydroartemisinin (DHA) has been investigated as an innovative tumor therapeutic agent. Herein, a DHA dimeric prodrug bridged with disulfide bond as linker (DHA2-SS) has been designed and synthesized....

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מידע ביבליוגרפי
Main Authors: Yawei Li, Qing Pei, Baiji Cui, Hongmei Zhang, Liu Han, Wenqing Li, Wenhe Zhu, Xianmin Feng, Zhigang Xie
פורמט: Article
שפה:English
יצא לאור: BMC 2021-12-01
סדרה:Journal of Nanobiotechnology
נושאים:
גישה מקוונת:https://doi.org/10.1186/s12951-021-01200-z